The research group Green Chemistry and Enabling Technologies is part of the Department of Amino acids, Peptides and Proteins of the Institut des Biomolécules Max Mousseron (IBMM) headed by Prof. Pascal Dumy. Located on the campus Triolet of the University de Montpellier, our team devotes its activities towards the development of a more sustainable chemistry, by using modern synthesis technologies, such as mechanochemistry, continuous flow and microwaves. These approaches enable the efficient and eco-responsible preparation of organic molecules, organometallics and materials, by using solvent-free synthesis, alternative solvents and catalysis. The molecules, synthesized in an innovative way, find applications in medicinal chemistry, catalysis and depollution.
Mechanochemistry opens the way to nucleotide synthesis
Collaborative work between the "Nucleosides and Phosphoryl Effectors" and "Green Chemistry and Enabling Technologies" research groups from IBMM has shown the positive impact of mechanochemistry on dinucleotide synthesis.
The ball milling technique not only limits the use of solvents and toxic reagents, but also reduces the amounts of by-products generated during the synthesis of dinucleosides 5',5'-polyphosphates (DNP) so as to facilitate purification, a critical point in nucleotide chemistry.
This gentle, fast and efficient approach offers new perspectives for the synthesis of nucleotide conjugates and analogues.
Link to the publication.
Full program here : https://www.gcande.org/program/
Mechanochemistry, reactive extrusion, continuous flow: 3 "Chemical Innovations That Will Change Our World" says IUPAC
The International Union of Pure and Applied Chemistry (IUPAC) has identified emerging technologies in Chemistry with potential to make our planet more sustainable. Among these are mechanochemistry, reactive extrusion and continuous flow chemistry. Forerunner particularly in the field of mechanochemistry, the Green Chemistry and Enabling Technologies team at Institute of Biomolecules Max Mousseron has also developed expertise in the fields of continuous flow chemistry and reactive extrusion, which makes it a team of the cutting edge of innovations in green chemistry!
- Mechanochemistry Summer School
Frédéric Lamaty and Xavier Bantreil are invited to present their work at the Mechanochemistry Summer School organized by the University of Sussex (UK) on July 5th 2019 in the framework of the LabFact project « Transforming Laboratories into Factories ».
Check the program here.
Recent scientific interests